Wilmington PharmaTech Continues Expansion with Significant Investment from Curewell Capital

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Wilmington PharmaTech Appoints Seasoned Commercial Leader to Drive Growth

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Integrated Contract Research, Development and Manufacturing Organization (CRDMO). Better Results, Faster.

We provide end-to-end support across the entire drug development lifecycle from small molecule APIs, combining the deep science of a Contract Research Organization (CRO) with the fast efficiency of a Contract Development and Manufacturing Organization (CDMO).

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Our seasoned team of medicinal chemistry experts have decades of specialized experience in solving the most complex synthetic challenges. For more than 20 years, we have designed hundreds of compound analogs and facilitated the synthesis of thousands of variants in support of target identification through lead optimization, across therapeutic areas. Wilmington PharmaTech has participated in rescuing many promising molecules that other contract providers could not develop.

In addition to chemical synthesis solutions, through our partner network, we can also coordinate other services supporting drug metabolism and pharmacokinetics (DMPK), safety, toxicology, product development and clinical trial support.

We provide Better Science Faster! For more than two decades, Wilmington PharmaTech has invested in creating deep scientific experience in chemical development for IND-enabling, seamless support. This includes process development and process scale up, through to cGMP supply. Our facility capabilities are purposefully designed to handle the full range of drug substance challenges, including multi-chiral center, OEB 5 HPAPI (e.g., for cytotoxic compounds and antibody-drug conjugate (ADCs)), continuous-flow processing, controlled drug substance (CDS), and peptides. Our capabilities include:

  • API synthesis
  • HPAPI dedicated suites
  • Process development and optimization
  • Process scale up
  • Analytical method development, validation and ICH stability programs
  • API impurity services
  • Robust IND-enabling services

We continuously invest to keep our laboratories and cGMP suites current, and well-equipped, including the recent addition of scalable purification solutions for chiral and achiral separations. Our advanced purification services include racemates and atropisomers with the same cycle used for the purification of both chiral and achiral molecules.

Proven expertise to accelerate your discovery program through target identification, scaffold synthesis, and lead optimization.

  • IND-enabling to small-scale commercial pilot plant for API production
  • High-potency API (HPAPI) handling
  • Capacity from large-scale cGMP labs to pilot suites

We offer flexible sourcing and support options to accelerate milestones, scale up production from pre-clinical to commerical volumes, optimize manufacturing productivity, and drive cost-efficiency.

Whether for in-process, release, or stability testing, Wilmington PharmaTech provides a comprehensive suite of analytical testing capabilities, including:

  • Analytical method development and validation
  • Full cGMP release for both clinical and commercial API
  • Non-GXP and GLP testing
  • Reference Standards, including preparation, qualification, and distribution standards for intermediates and APIs
  • Identification of impurities and preparation for qualification, retesting and distribution of impurity standards
  • Full ICH stability studies, including trace impurity analysis
  • Designated QA office and documentation storage
  • Genotoxicity impurity services including: assessment reports; reference compounds; Ames test (via partner); control strategies; analytical method development, qualification and validation; sub-ppm trace impurity analysis for RSMs, APIs and intermediates; final technical reporting.

With a wealth of expertise and a combined 20+ years of experience, Wilmington PharmaTech provides comprehensive solid-state chemistry support to optimize your API’s form. Our services include:

  • Salt selection and polymorph screening
  • Crystallization optimization

Wilmington PharmaTech has supported the registration of more than 30 patents on behalf of our customers. We have developed more than 300 API candidates, and supported upwards of 180 investigational new drugs (INDs), and 7 new drug applications (NDAs)

At the request of many clients, Wilmington PharmaTech has created a unique catalogue of difficult to synthesize starting materials and analogues available at Kg scale to facilitate discovery and IND enabling activities. A pdf list of these compounds is available upon request.

Wilmington PharmaTech by the numbers

0+ years

of cGMP manufacturing

0+ API

candidates developed

> 0 patents

enabling client products

> 0

IND submissions, and counting…

“

Our foundation is best-in-class API development backed by a proven record of customer value creation.

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Harry Li, Ph.D,

CEO & Founder of Wilmington Pharmatech Company

Careers

At Wilmington PharmaTech, we are constantly looking to hire talented and experienced synthetic and analytical chemists who have a passion for research and development.

Email us at Talent@WilmingtonPharmaTech.com

Sr. Synthetic Organic Chemists, Ph. D.

Candidates will design and perform experiments in order to develop new processes for the manufacture of new drug candidates.

Apply now

Quality Assurance - Director

The role includes leading and overseeing Document Review & Batch Release, QA Product Management, Customer Complaints, CAPAs and more.

Apply now

Sr. Analytical Chemists - B.S., M.S, Ph.D.

Follows/executes written procedures/protocols with minimal supervision and completes notebook and verification with accuracy.

Apply now

Chemical Process Engineer

Candidates are supporting the manufacturing team that creates drug products by working closely with process chemists, pilot plant operators, and QA colleagues.

Apply now

Chemical Process Engineer

Candidates are supporting the manufacturing team that creates drug products by working closely with process chemists, pilot plant operators, and QA colleagues.

Apply now

Sr. Business Development Director

Wilmington PharmaTech (WPT) is seeking a results-driven Sr. Business Development Director based in the Western United States ideally to spearhead new client acquisition and territorial growth for its API development and manufacturing services. This role focuses on building a robust sales funnel, leading complex negotiations, and partnering with internal technical teams to deliver high-value solutions to customers. Successful candidates must have at least seven years of contract API or CDMO sales experience and a chemistry or scientific degree, alongside a demonstrable history of exceeding business targets.

Apply now

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